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Test Code LAB581 Zinc, Serum

Important Note


PRMC OutReach Serum Collection Instructions

1.   Prepare the patient for phlebotomy, following your normal protocol, using alcohol to disinfect the collection site. Do not use iodine-containing products.

2.   Draw blood in a plain (no additive, red on label) royal blue Vacutainer (Supply T184) tube

3.   Allow the specimen to clot for at least 30 mins but serum must be separated from cells within 2 hrs.

4.   Centrifuge the specimen to separate serum from cellular fraction.

5.   Attach a specimen identification label to a Mayo Metal-Free Specimen Vial (Supply T173).

6.   Remove the collection tube stopper. Carefully pour the serum into the vial, avoiding transfer of the cellular components of blood.

***Do not insert a pipette into the serum to accomplish transfer.

***Do not ream the specimen with a wooden stick to assist with serum transfer.

***Blood from a dialysis patient on heparin may produce an uncoagulated serum that forms a fibrin clot after centrifugation. Pour off serum as soon as possible, and repeat centrifugation step if more serum is needed.

7.   If there are cells in the poured off specimen, centrifuge the tube and pour off serum into a second Mayo Metal-Free Specimen Vial (Supply T173).

8.   Place the cap on the vial tightly and send the specimen to the laboratory at the temperature indicated in the test’s transport instructions.

Additional Codes

Mayo Test ID




Reporting Name

Zinc, S

Useful For

Detecting zinc deficiency

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type


Specimen Required

Patient Preparation: High concentrations of gadolinium, iodine, and barium are known to interfere with most metals tests. If gadolinium-, iodine-, or barium-containing contrast media has been administered, a specimen should not be collected for 96 hours.


-Metal Free B-D Tube (No Additive), 6 mL (T184)

-Metal Free Specimen Vial (T173)

Collection Container/Tube: 6-mL Plain, royal blue-top Vacutainer plastic trace element blood collection tube

Submission Container/Tube: 7-mL Mayo metal-free, screw-capped, polypropylene vial

Specimen Volume: 0.8 mL

Collection Instructions:

1. Allow the specimen to clot for 30 minutes after collection; then centrifuge the specimen to separate serum from the cellular fraction. Serum must be removed from cellular fraction within 4 hours of specimen collection. Avoid hemolysis.

2. Remove the stopper. Carefully pour specimen into a Mayo metal-free, polypropylene vial, avoiding transfer of the cellular components of blood. Do not insert a pipet into the serum to accomplish transfer, and do not ream the specimen with a wooden stick to assist with serum transfer.

3. See Trace Metals Analysis Specimen Collection and Transport in Special Instructions for complete instructions.

Specimen Minimum Volume

0.2 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 28 days METAL FREE
  Ambient  28 days METAL FREE
  Frozen  28 days METAL FREE

Reference Values

0-10 years: 0.60-1.20 mcg/mL

≥11 years: 0.66-1.10 mcg/mL

Day(s) and Time(s) Performed

Monday; 2 p.m.

Tuesday through Friday; 5 p.m.

Saturday; 2 p.m.

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information


LOINC Code Information

Test ID Test Order Name Order LOINC Value
ZNS Zinc, S 5763-8


Result ID Test Result Name Result LOINC Value
8620 Zinc, S 5763-8

Method Name

Dynamic Reaction Cell-Inductively Coupled Plasma-Mass Spectrometry (DRC-ICP-MS)


If not ordering electronically, complete, print, and send a General Request (T239) with the specimen.