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Test Code LAB000 - Enter Specimen type, Source, and Test Name VHL Gene, Full Gene Analysis, Varies

Additional Codes

Mayo test code: VHLZ

Useful For

Diagnosis of suspected von Hippel-Lindau (VHL) disease

 

Diagnosis of suspected VHL-related hereditary erythrocytosis

Method Name

Polymerase Chain Reaction (PCR) Followed by DNA Sequence Analysis and Gene Dosage Analysis by Multiplex Ligation-Dependent Probe Amplification (MLPA)

Reporting Name

VHL Gene, Full Gene Analysis

Specimen Type

Varies


Shipping Instructions


Specimen preferred to arrive within 96 hours of draw.



Specimen Required


Patient Preparation: A previous bone marrow transplant from an allogenic donor will interfere with testing. Call 800-533-1710 for instructions for testing patients who have received a bone marrow transplant.

Specimen Type: Whole blood

Container/Tube:

Preferred: Lavender top (EDTA) or yellow top (ACD)

Acceptable: Any anticoagulant

Specimen Volume: 3 mL

Collection Instructions:

1. Invert several times to mix blood.

2. Send specimen in original tube.


Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Varies Ambient (preferred)
  Frozen 
  Refrigerated 

Reference Values

An interpretive report will be provided.

Day(s) and Time(s) Performed

Performed weekly; Varies

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

81404-VHL (von Hippel-Lindau tumor suppressor) (eg, von Hippel-Lindau familial cancer syndrome), full gene sequence

81403-VHL duplication/deletion

LOINC Code Information

Test ID Test Order Name Order LOINC Value
VHLZ VHL Gene, Full Gene Analysis 82533-1

 

Result ID Test Result Name Result LOINC Value
37453 Result Summary 50397-9
37454 Result 82939-0
37455 Interpretation 69047-9
37456 Additional Information 48767-8
37457 Specimen 31208-2
37458 Source 31208-2
37459 Released By 18771-6

Forms

1. New York Clients-Informed consent is required. Document on the request form or electronic order that a copy is on file. The following documents are available in Special Instructions:

-Informed Consent for Genetic Testing (T576)

-Informed Consent for Genetic Testing-Spanish (T826)

2. VHL Gene Testing Patient Information (T641) in Special Instructions

3. If not ordering electronically, complete, print, and send an Oncology Test Request (T729) with the specimen.